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Tegeler CH, Lee S, Tegeler C, and Shaltout H. (2013). Correlation between temporal lobe EEG asymmetry and heart rate variability. Neurology. Feb 12, 2013; 80 (Meeting abstracts 1): P03:031.

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Tegeler CH, Tegeler CL, Kumar SR, Turner DP, Gerdes L, Lee SW, and Houle TT. (2013). Randomized, placebo-controlled pilot trial of a novel, noninvasive electroencephalic feedback-based intervention, HIRREM, for alleviation of episodic migraine. Cephalalgia: Abstracts of the 2013 International Headache Conference. June; 33(8) Supplement: 99-100.

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Disturbances of neural oscillation patterns have been reported with many disease states. We introduce methodology for HIRREM (high-resolution, relational, resonance-based electroencephalic mirroring), also known as Brainwave Optimization, a noninvasive technology to facilitate relaxation and autocalibration of neural oscillations. HIRREM is a precision-guided technology for allostatic therapeutics, intended to help the brain calibrate its own functional set points to optimize fitness.

Brain State Technologies is pleased to announce the publication of new research into their proprietary HIRREM technology in the peer reviewed interdisciplinary journal

The purpose of this paper is to describe technical and theoretical aspects of Brainwave Optimization™, also known as High-resolution, Relational, Resonance-based Electroencephalic Mirroring™ (HIRREM™). HIRREM is an innovative, non-invasive approach to facilitating greater self-regulatory capacity for, by and through the human brain. The approach may be conceived as a high-resolution electronic mirror that reflects the brain’s activity back to itself in real-time.

In terms of technological lineage, Brainwave Optimization™ (more formally known as High-resolution, Relational, Resonance-based Electroencephalic Mirroring or HIRREM) can be considered as an advance on the methodology of electroencephalographic biofeedback (also known as “EEG biofeedback” or “neurofeedback.”) For purposes of this discussion, we will generally refer to it as “EEG biofeedback.”

Vijendra K. Singh and Lee Gerdes conducted a study in which clients with symptoms of PTSD, depression, and anxiety experienced Brainwave Optimization, a technology that optimizes brainwaves in real-time to achieve balance and harmony in the brain. After administering Brainwave Optimization over the course of several personalized sessions, Dr. Singh and Mr. Gerdes observed alleviation of depressive and anxiety tendencies and noticeable improvements in quality of life in all of the clients. As a result, they recommend Brainwave Optimization as a viable approach to help with PTSD.

Vijendra K. Singh and Lee Gerdes performed a study of four subjects who were exhibiting symptoms of major depressive disorder. The goal of the study was to overcome the clients' depression, alleviate anxiety, and achieve physical health and balance, among other things. Following individual assessments, Dr. Singh and Mr. Gerdes administered Brainwave Optimization™, resulting in positive responses from all of the subjects. All of the subjects improved their test scores for depression and anxiety, and showed reductions in depressive tendencies, anxiety, substance abuse, and sleep deprivation.

Vijendra K. Singh, Ph.D., Director of Research at Brain State Technologies, discusses the importance of recognizing neurological diseases and mental illnesses, such as autism spectrum disorders and Alzheimer's disease, as autoimmune diseases. Dr. Singh argues that the patient population with these brain diseases "must be included in all future epidemiological studies" in order to get the full picture of autoimmune diseases' impact on human health.

Lee Gerdes and Vijendra K. Singh performed a preliminary study on cognition of six patients with Alzheimer's disease or Parkinson's disease. After assessing each client's brain, Mr. Gerdes and Dr. Singh used Brainwave Optimization, to correct patients' brain imbalances over the course of 10-15 personalized individual sessions. All of the subjects showed improved neurological and behavioral characteristics, including improved cognitive functions.

This report depicts individual results achieved in the Prescott, Arizona Yavapai County trial using Brainwave Optimization sessions with repeat offenders. Arrests were for possession of illegal drugs or drug paraphernalia, petty theft, disturbing the peace, assault, and other miscellaneous crimes.

The VA has seen a tenfold increase in PTSD cases in the last year. According to the VA, more than 37,000 Vets of Iraq and Afghanistan are suffering from Mental Health disorders, and more than 16,000 have already been diagnosed with PTSD.

"After Brainwave Optimization with Brain State Technologies® (BST) I’m sleeping better than ever and my irritability/anger has decreased significantly,” says SGT. Dan F., U.S. Army 10th Mtn. Div. “The best thing about this technology is that I never had to mention a thing about my combat experiences as BST is not a ‘talk’ solution."

Brainwave Optimization was conducted with six inmates, all with history of violent crimes and drug abuse. The PTSD Checklist (Stressor Specific Version, or PCL-S) was administered pre and post-Brainwave Optimization. All reported improvements in anger management, focus/attention, sense of happiness, overcoming depression and ability to interact socially.

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